A Gel-Based Proteomic Comparison of Human Cerebrospinal Fluid between Inflicted and Non-Inflicted Pediatric Traumatic Brain Injury
نویسندگان
چکیده
منابع مشابه
A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury.
Traumatic brain injury (TBI) is the most common cause of traumatic death in infancy, and inflicted TBI (iTBI) is the predominant cause. Like other central nervous system pathologies, TBI changes the composition of cerebrospinal fluid (CSF), which may represent a unique clinical window on brain pathophysiology. Proteomic analysis, including two-dimensional (2-D) difference in gel electrophoresis...
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We report a one year old boy with clinical and neuroimaging findings of inflicted traumatic brain injury. The clinicians often overlook this form of physical abuse. The family structure also plays an important role in neglecting this form of problem.
متن کاملWhich clinical features distinguish inflicted from non-inflicted brain injury? A systematic review.
AIM A systematic review of the scientific literature to define clinical indicators distinguishing inflicted (iBI) from non-inflicted brain injury (niBI). METHODS An all language literature search of 20 electronic databases, websites, references and bibliographies from 1970-2008 was carried out. Relevant studies were independently reviewed by two trained reviewers, with a third review where re...
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Objective Pneumocephalus is a rare complication that often occurs after traumatic skull base injury, leading to morbidity and mortality. Material and Method We present the case of a 42-year-old healthy man who injured himself when he stuck a metal stick into his left nasal cavity to relieve prolonged nasal obstruction. Immediate cerebrospinal fluid rhinorrhea and subsequent meningitis and pne...
متن کاملUsing Serum and Cerebrospinal Markers: A Possible Screening Tool Identification of Inflicted Traumatic Brain Injury in Well-Appearing Infants
OBJECTIVE. Inflicted traumatic brain injury (iTBI) is the leading cause of death from TBI in infants. Misdiagnosis of iTBI is common and results in increased morbidity and mortality. Biomarkers may be able to assist in screening infants who are at high risk for iTBI and whose injury might otherwise be missed. We investigated whether serum and/or cerebrospinal fluid (CSF) concentrations of neuro...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2007
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2006.0061